16S Inferred Metagenomic Function

Due to deep sequencing and complex computational requirements, Whole Metagenomic or Metatransciptomic Functional Profiling, which directly sequences and profiles the differential genes or transcripts involved in the specific experiment, can be cost prohibitive for some research groups.

As an alternative such direct functional profiling, we have introduced 16S Inferred Metagenomic Function. This new offering utilizes 16S community profiles to estimate the metagenomic function of a microbial community. In this computational approach to functional composition, 16S sequencing reads are mapped to known genomes within a reference database. With more than 7,500 bacterial genomes in the Second Genome database, our approach accesses more bacterial genomes than any inferred functional approach published to date. Reported in a similar fashion as the Whole Metagenomic Functional Profiling Services, this new computational approach provides a cost-effective solution for gaining insight into the estimated functional potential of a community.