Second Genome proprietary drug delivery system via Lactococcus Lactis (L. lactis)

Why L. lactis delivery system

  • Clinical success with other L. lactis drug delivery systems (ActoBio™).
  • Direct gut delivery, non-systemic.
  • Lactococcus Lactis L. lactis is Generally Regarded As Safe (GRAS).
  • Clear regulatory pathway.
  • Probiotic.

GI tract is rich in proteases that makes it very challenging to delivery therapeutics to the gut. Our drug delivery vehicle ensures that peptide(s)/protein(s) reach its target.

Our Engineered L. lactis Drug Delivery System is a Second Genome proprietary drug delivery platform designed to deliver therapeutic proteins or peptides directly to the gut mucosal tissue. This drug delivery system is being utilized to deliver SG-2-0776 directly to the gut mucosal tissue and will also be applicable as a delivery system future programs that require non-systemic direct delivery to the digestive tract. L. lactis as a delivery system has been successfully used in the clinic, it allows for non-systemic direct gut delivery, is Generally Regarded as Safe (GRAS), has a clear regulatory pathway with many regulatory agencies.